Panama City Top 102. Casco Viejo (or Antiguo)
Reminiscent of Old San Juan, this elegantly crumbling old quarter of the city dates to the late 1600s. Now a UNESCO Heritage Site, it’s undergoing renovations daily, with lovingly restored buildings abutting crumbling shells, and hip wine bars and coffee shops sharing real estate with art shops and churches from the 1670s. An afternoon stroll of the cobblestone streets is a must.